Medicine

Last updated on: May 9th, 2021

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You’re looking at an interactive case study from Prognosis: Your Diagnosis (one of four distinct learning formats available in Clinical Odyssey). Try it out, and have fun improving your clinical skills.

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A 42 year old man presents with numbness and a tingling sensation in both lower limbs, associated with generalised weakness and fatigability for 3 months.


He also experienced occasional malodorous, bulky stools and lost 8 kg of weight during the preceding year. There was no history of alcohol abuse, rectal bleeding, or joint pains.


His full blood count shows a Hb of 8.7 g/dL and MCV of 112 fL. A blood film shows a megaloblastic anemia with hypersegmented neutrophils.


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