Draining the Swamp

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A 55-year-old man is evaluated in the hospital on day 10 of his admission for a primary right lower lobe lung abscess. He originally presented with a 3-week history of fever, productive cough with foul-smelling sputum, and weight loss. His medical history is significant for alcohol use disorder and poor dentition. Upon admission, he was started on intravenous ampicillin-sulbactam. Despite 10 days of directed antimicrobial therapy, he continues to experience daily fevers and worsening pleuritic right-sided chest pain. He denies any hemoptysis. He appears chronically ill, diaphoretic, and in mild respiratory distress. His temperature is 101.8°F (38.8°C), blood pressure is 110/70 mmHg, heart rate is 112 bpm, and respiratory rate is 22/min with an oxygen saturation of 93% on room air.

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