Last updated on: August 25th, 2021

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You’re looking at an interactive case study from Prognosis: Your Diagnosis (one of four distinct learning formats available in Clinical Odyssey). Try it out, and have fun improving your clinical skills.



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A 26-year old primigravid woman of 30 weeks gestation presents with worsening non-pruritic jaundice for one week. There is no associated abdominal pain, nausea, vomiting, or fever, and her antenatal period has otherwise been uneventful.

Her medical history is unremarkable other than a few episodes of jaundice during her teens, all of which resolved spontaneously after a few days. These were not investigated at that time.

She neither smokes nor drinks. A hepatitis panel is negative for hepatitis A IgM antibodies, hepatitis B surface antigen, hepatitis B IgM core antibody, and hepatitis C antibodies.

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