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A 62-year-old man presents for a routine follow-up appointment, four months after undergoing a deceased donor kidney transplant for end-stage renal disease. He is maintained on a standard triple-immunosuppression regimen. Laboratory studies performed one week prior to his visit revealed elevated aminotransferases. He reports mild fatigue which he attributes to his recovery but denies fever, jaundice, abdominal pain, nausea, or any changes in his urine or stool color. He has not traveled recently. He is an avid home cook and frequently purchases pork, including specialty liver sausages, from a local farm, which he sometimes consumes undercooked. His current medications include tacrolimus, mycophenolate mofetil, and a low dose of prednisone. Initial laboratory studies on presentation are as follows:


AST: 155 U/L (10-40)

ALT: 212 U/L (7-56)

Alkaline Phosphatase: 115 U/L (40-120)

Total Bilirubin: 0.9 mg/dL (0.1-1.2)

Creatinine: 1.5 mg/dL (baseline 1.4)

Tacrolimus level: 7.8 ng/mL (target 5-10)

WBC: 6,800/mm3 (4,500-11,000)

Hemoglobin: 11.8 g/dL (13.5-17.5)

Platelets: 185,000/mm3 (150,000-400,000)